Postboks for prosjektet Studier av svikt og overproduksjon i testikler, eggstokker og binyrebark

Hei, vi ønsker innspill fra pasienter, pårørende og helsearbeidere om kommentarer til pågående prosjekter som er omtalt på denne internettsiden eller nye ideer til prosjekter. Målet er å bygge en database med forsknings- og samfunnsspørsmål som er relevant for forskningsprosjektet og som kan brukes av forskere og brukere i senere faser av prosjektet.

I boksen nedenfor kan du komme med ideer til oss.

Postboks for prosjektet Diabetes og stamceller

Hei, vi ønsker innspill fra pasienter, pårørende og helsearbeidere om kommentarer til pågående prosjekter som er omtalt på denne internettsiden eller nye ideer til prosjekter. Målet er å bygge en database med forsknings- og samfunnsspørsmål som er relevant for forskningsprosjektet og som kan brukes av forskere og brukere i senere faser av prosjektet.

I boksen nedenfor kan du komme med ideer til oss.

5th Annual BSCC Conference, 2-3 October 2019

It is a pleasure to invite you to the fifth annual BSCC conference. We are currently working on the final program and have already some great speakers from Bergen, Oslo and abroad.

The meeting will take place at Hotel Scandic Ørnen in the center of Bergen on October 3rd and 4th, starting with lunch on the 3rd and finishing in the afternoon of the 4th. Registration is open already, participation is free for BSCC members.

For details and registration, see BSCC homepage:
https://helse-bergen.no/arrangementer/bscc-5-annual-meeting-2019-10-03

We will keep the exciting concept for this years “Lightning talks” presentation sessions and a price for best presentation. Check it out on the events webpage.

We hope you can all participate! Please share this information with colleagues and students who might be interested.

Best regards from BSCC!

Organising Committee:

Xiao Liang
Luiza Ghila
Niyaz Al-Sharabi
Anne Margrete Øyan

 

Thesis Defence: Heidrun Vethe

We are gladly announcing the public defence of Heidrun’s PhD thesis on Friday, 10th of May 2019:

Title: “In vitro modulation of pancreatic islet cell fate characterized by mass spectrometry-based proteomics”

1. opponent: Professor, Per-Ola Carlsson, Uppsala University, Sweden

2. opponent: Dr. rer. nat. Natalia Soshnikova, Institute of Molecular Biology gGmbH (IMB), Germany

3. member of the committee: Professor, Jørn V. Sagen, University of Bergen

The thesis defence will be led by Professor Silke Appel (University of Bergen).

The presentation is open for anyone interested!

Date and time: 10.05.2019 at 11.1515.30
Place: Auditorium, Armauer Hansens Hus, Haukelandsveien 28

Meetings Calendar 2019

Please add your name to the respective meeting that you are attending this year by editing this post, write a comment below or send me an e-mail 🙂 Also, please add any interesting conference or course you might know. 

JANUARY

27-31: Cellular Plasticity: Reprogramming, Regeneration and Metaplasia (J3),

Keystone Resort,  Colorado, USA,

Scientific Organizers: Jason C. Mills, Maike Sander and Ben Z. Stanger

DEADLINES:
*All deadlines end at 11:59 PM US Mountain Standard Time
Scholarship Deadline: Oct 3, 2018
Discounted Abstract Deadline: Oct 3, 2018
Abstract Deadline: Oct 25, 2018
Discounted Registration Deadline: Nov 28, 2018

FEBRUARY

1: UCLA Annual Stem Cell Symposium: B2B – Bench to Bedside

Los Angeles, USA

 

20-22:  ISSCR Stem Cell and Organoids in Disease and Development

 Amsterdam, Netherlands

Abstract Submission Deadline: Wednesday, 7 November, 2018 at 11:59 PM CT USA

Online registration will close on Thursday, 14 February, 2019

Participants: YNGVILD, LAURENCE

MARCH

21-23: SY-STEM: Symposium for the next generation of stem cell researchers

 Vienna, Austria

Abstract Submission Deadline: 4 February 2019

Registration Deadline: 4 March 2019

27-29: Developmental and Cell Biology of the future

Paris, France

Abstract Submission Deadline: February 10th 2019

Participants: LUIZA; SIMONA

APRIL

1-3: 3rd Joint EASD Islet Study Group and Beta-Cell Workshop

Oxford, UK

Abstract Submission Deadline: Friday 1st February 2019 5pm GMT

Early Bird Registration deadline: 31st December 2018

Online registration will close on 1 February 2019

Participants: THOMAS

MAY

2-3: Danish Stem Cell Conference

Vejle, Denmark

Online registration will close on 15 March 2019

JUNE

26-29: ISSCR 2019 Annual Meeting

Los Angeles, USA

Abstract Submission Deadline: 6 February 2019
Online registration will close on: 13 March (Early); 08 May (Late)

JULY

25-29: Society for Developmental Biology (SDB) 78th Annual Meeting

Boston, Massachusetts, USA

Abstract Submission Deadline: April 15, 2019
Early Registration Deadline: May 13, 2019

AUGUST

 

SEPTEMBER

 

OCTOBER

23-26 European Developmental Biology Congress

Alicante, Spain 

Abstract Submission Deadline: June, 2nd 2019
Registration Deadline: 31st July 2019

NOVEMBER

12-13: 7th International Stem Cell Meeting

Tel Aviv, Israel

Abstract Submission Deadline: TBA
Registration Deadline: TBA

DECEMBER

 

Key Opinion Leaders Meeting on Stem Cells Derived Beta Cells

Second IPITA-JDRF-HSCI Key Opinion Leaders Meeting on Stem Cells Derived Beta Cells was held at the Joseph B. Martin Conference Center at Harvard Medical School in Boston, MA, USA from May 7- 8, 2018.

Our research group was represented by:

  • Helge Ræder as an invited speaker in the 2nd session “TRANSCRIPTOMICS, PROTEOMICS AND MICROFLUIDICS: WHAT CAN THEY TEACH US?”
    and talked about strategies currently under development for proteomics analyses with a focus on iPSC-derived beta-like cells.
  • Heidrun Vethe
  • Laurence Hoareau

The workshop program offered world-renown expert speakers, i.e. Douglas Melton, George M. Church, Mahendra S. Rao, Hiro Nakauchi, Matthias Hebrok, Kevin D’Amour, presenting highly innovative science with state of the art developments.

Workshop topics included:

  • Identifying persistent challenges such as developing beta cells with full physiologic function
  • Understanding the potential role of genome engineering to modify cells for therapeutic advantage
  • Identifying optimal transplant platforms and encapsulation technologies
  • Developing effective approaches to escape allo-, and autoimmunity
  • Update on competing technologies including blastocyst complementation and gene edited xenografts
  • Presenting recent preclinical and clinical trial results.

Helge discussed about the need for complementary characterising methods, such as proteomics, in particular since there is a growing evidence of biologically relevant differences when comparing transcriptomics and proteomics data. These discrepancies arise from a difference in the dynamics of RNA and protein products. He also showed some examples of the use of proteomics methods in conjunction with cell biology techniques in our studies of patient-derived iPSC cells and of different cell stages during targeted differentiation towards Beta-like Cells.

Meetings Calendar 2018

Please add your name to the respective meeting that you are attending this year by editing this post, write a comment below or send me an e-mail 🙂 Also, please add any interesting conference or course you might know. 

FEBRUARY

4-8: Frontiers in Islet Biology, Keystone Meeting, Keystone Resort, Colorado, USA: THOMAS, MANUEL

APRIL

18-20: Nordic Proteomics Conference, NPC 2018, Radisson Blu Royal Hotel at the Harbor in Bergen: HELGE

MAY

7-8: 2nd Opinion Leaders Meeting on Stem Cell Derived Beta Cells, Boston, MA, USA: HELGE, HEIDRUN, LAURENCE

27-31: The Stem Cell Niche Conference (Novo Nordisk Fonden / DanStem)

JUNE

5-6: Manufacturing and Testing of Pluripotent Stem Cells: IABS and CIRM, Los Angeles, CA

17-18: Stem Cells in Disease Modelling and Drug Discovery, Melbourne, Australia

20-23:  ISSCR Melbourne, Australia: LAURENCE

JULY

17-18 11th annual Business of Regenerative Medicine: Innovation, Clinical Translation, and Entrepreneurship Symposium, Perelman School of Medicine, Philadelphia, USA

AUGUST

29-31: Stem Cell Dynamics Throughout Life: From Development to the Adult; Basel, Switzerland

29-30: BSSC Meeting, Bergen, Norway: SIMONA, LUIZA; LAURENCE, MANUEL; THOMAS; HEIDRUN; YNGVILD, HELGE

SEPTEMBER

10-13: Organoids: Modelling Organ Development and Disease in 3D Culture, Heidelberg, Germany

10-13: BSDB: Embryonic-Extraembryonic Interactions – from genetics to environment, Oxford, UK

12-14: European WNT Meeting, Heidelberg, Germany

15-19: The molecular and cellular basis of regeneration and tissue repair, Valetta, Malta: SIMONA, LUIZA

17-21: EMBL Course: Genome Engineering: CRISPR / Cas, Heidelberg, Germany

18-21: 10th Microencapsulation Training School. Trondheim, Norway: THOMAS, MANUEL

19-21: 6th Cambridge International Stem Cell Symposium, Cambridge, UK

23-26: From stem cells to human development, Surrey, UK (a conference from the journal Development)

27-29: The 57th Annual European Society for Paediatric Endocrinology Meeting Athens, Greece

OCTOBER

1-5: EASD Berlin, Germany

5-7: EASD Islet Study Group Meeting, Potsdam, Germany [SESSION:Comparison between primary human beta cells and the EndoC-βH1 beta-cell line]: THOMAS

16-19: Changing the Face of Modern Medicine: Stem Cells and Gene Therapy, Lausanne, Switzerland

17-18: 5th Geneva Diabetes Centre Symposium and G2L2 Meeting, Geneva, Switzerland: SIMONA, LUIZA

23-24: New York Stem Cell Foundation Research Institute’s 2018 Stem Cell Conference, New York, NY

26-27: 5th BBDC-JOSLIN-UCPH Conference on Prevention of Beta Cell Dysfunction in Type 1 and Type 2 Diabetes: Role of Inter-organ Communication, Copenhagen, Denmark THOMAS, SIMONA, LUIZA

NOVEMBER

7-10:  Joint Meeting of the Portuguese, Spanish and French Societies for Developmental Biology, Porto (Portugal)

19-23: Conferences Jacques Monod: Modeling cell fate, Roscoff, France

DECEMBER

2-4: Cell Symposia: Translation of Stem Cells to the Clinic, Challenges and Opportunities, Cedars-Sinai, California, USA

3-4: Stem Cells and Regenerative Medicine Conferences in Valencia, Spain

Invited speaker: Natalia Soshnikova

We have the pleasure of hosting Dr. Natalia Soshnikova from the Institute of Molecular Biology gGmbH (IMB) in Mainz, Germany. She will talk about the molecular mechanisms of intestinal stem cell specification during development.

More details about her research here: Soshnikova Lab

Date: Thursday 18th of January
Time: 10:30 – 11:10 + discussions
Place: BUS1: Meeting-room Pankreas (6th floor, KGJ for Diabetes)

Microsoft Word - SEMINAR-Natalia.docx
Some Selected Papers produced by the Soshnikova lab:

  • Dzama MM, Nigmatullina L, Sayols S, Kreim N and Soshnikova N (2017). Distinct populations of embryonic epithelial progenitors generate Lgr5+ intestinal stem cells. Dev Biol, pii: S0012-1606(17)30576-6. doi: 10.1016/j.ydbio.2017.10.012
  • Kazakevych J, Sayols S, Messner B, Krienke C and Soshnikova N (2017). Dynamic changes in chromatin states accompany specification of the adult intestinal stem cells. Nucleic Acids Res, 45(10):5770-5784. doi: 10.1093/nar/gkx167
  • Nigmatullina L, Norkin M, Dzama MM, Messner B, Sayols S, Soshnikova N (2017). Id2 controls specification of Lgr5+ intestinal stem cell progenitors during gut development. EMBO J, 36: 869-885. doi: 10.15252/embj.201694959 (recommended by F1000Prime)
  • Jung H, Mazzoni EO, Soshnikova N, Hanley O, Venkatesh B, Duboule D, Dasen JS (2014). Evolving Hox activity profiles govern diversity in locomotor systems. Dev Cell, 29, 171-187
  • Schorderet P, Lonfat N, Darbellay F, Tschopp P, Gitto S, Soshnikova N, Duboule D (2013). A genetic approach to the recruitment of PRC2 at the HoxD locus. PLoS Genet, 9, e1003951
  • Montavon T, Soshnikova N, Mascrez B, Joye E, Thevenet L, Splinter E, de Laat W, Spitz F and Duboule D (2011). A regulatory archipelago controls Hox genes transcription in digits. Cell, 147, 1132-1145
  • Soshnikova N, Montavon T, Leleu M, Galjart N and Duboule D (2010). Functional analysis of CTCF during mammalian limb development. Dev Cell, 19, 819-830
  • Soshnikova N and Duboule D (2009). Epigenetic temporal control of mouse Hox genes in vivo. Science, 324, 1320-1323

Please share with your colleagues and students, and show your support by attending the seminar.